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Comparative analysis demonstrates enhanced pancreatic morphology after duodenojejunostomy in Zucker diabetic fatty rats, indicating potential benefits.
Malabsorptive (DJOS) or combination bariatric procedures (DJOS + SG) significantly enhance glycemic control in the rat model. These effects are accompanied by increased β-cell numbers and clustering, as well as enhanced β-cell proliferation and differentiation. Furthermore, acinar glandular tissue is increased, while pancreatic adiposity is reduced following bypass surgery.
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Schäfer et al. (2026) studied this question.
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