A Randomized, Double-blind, Split-face Trial Evaluating the Safety and Efficacy of a Serum Containing Plant Adaptogens Versus Moisturizing Lotion Pre- and Post-fractional Laser in Patients with Mild-to-moderate Photodamage.

Jacqueline Watchmaker; Diane B Nelson

January 1, 2026

A Randomized, Double-blind, Split-face Trial Evaluating the Safety and Efficacy of a Serum Containing Plant Adaptogens Versus Moisturizing Lotion Pre- and Post-fractional Laser in Patients with Mild-to-moderate Photodamage.

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Key Points

Significant reductions in dryness and erythema were observed with plant adaptogens serum.
Global skin healing and skin quality improved notably compared to the moisturizing lotion used.
Application was twice-daily, indicating a structured regimen for maximum efficacy at each treatment phase.
The double-blind, split-face trial design enhances reliability of the findings and minimizes bias.

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Implication

Randomized trial evaluates serum's effectiveness on skin healing in patients with mild-to-moderate photodamage, suggesting potential benefits over standard lotion.

Abstract

Twice-daily application of a serum containing plant adaptogens before and after non-ablative fractional laser treatment demonstrated significant reductions in dryness and erythema, and improvements in global skin healing and skin quality compared to ML.

A Randomized, Double-blind, Split-face Trial Evaluating the Safety and Efficacy of a Serum Containing Plant Adaptogens Versus Moisturizing Lotion Pre- and Post-fractional Laser in Patients with Mild-to-moderate Photodamage.

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A Randomized, Double-blind, Split-face Trial Evaluating the Safety and Efficacy of a Serum Containing Plant Adaptogens Versus Moisturizing Lotion Pre- and Post-fractional Laser in Patients with Mild-to-moderate Photodamage.

Key Points

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Implication

Abstract

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