A novel finding on sex-dependent diverse behavioral responses to the anticipation of a threat in a rat model of fear conditioning with the involvement of brain-derived neurotrophic factor (BDNF) in the prefrontal cortex | Synapse
March 3, 2026
A novel finding on sex-dependent diverse behavioral responses to the anticipation of a threat in a rat model of fear conditioning with the involvement of brain-derived neurotrophic factor (BDNF) in the prefrontal cortex
Key Points
Threat anticipation triggers diverse behavioral responses in male and female rats, highlighting sex differences.
Key evidence shows significant variations in behavior related to brain-derived neurotrophic factor levels.
Preclinical study utilizing a fear conditioning model assesses the role of BDNF in the prefrontal cortex.
These findings may enable further research on the neurobiological underpinnings of fear responses across sexes.