FNDC5/Irisin Mediates the Protective Effect of Resistance Exercise Against Myocardial Infarction-Induced Renal Injury by Improving Vascular Rarefaction in Mice | Synapse
March 3, 2026
FNDC5/Irisin Mediates the Protective Effect of Resistance Exercise Against Myocardial Infarction-Induced Renal Injury by Improving Vascular Rarefaction in Mice
Key Points
Irisin, a protein linked to exercise, plays a key role in reducing renal injury after myocardial infarction.
Mice showed improved vascular rarefaction and kidney function following resistance exercise training.
The study utilized a murine model to explore the effects of FNDC5 on organ protection.
Findings highlight the potential of exercise-induced factors in preventing kidney damage after heart attacks.