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The aim is to compare the cytotoxic and antioxidant effects of apricot fruit and traditional jam on healthy and cancer cell lines.

March 4, 2026Food and HealthOpen Access

Comparative evaluation of the cytotoxic and antioxidant effects of apricot (Prunus armeniaca L.) fruit and traditionally prepared apricot jam: Differential impacts on healthy and cancer cell lines

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The aim is to compare the cytotoxic and antioxidant effects of apricot fruit and traditional jam on healthy and cancer cell lines.
Cytotoxic effects assessed using MTT method on various cell lines (L929, A549, CaCo-2, Hep3B, MCF-7, PC-3)
Antioxidant capacity measured using DPPH, CUPRAC, and TEAC methods
Comparison of effects between the aqueous extract of apricot fruit and traditionally prepared jam at varying concentrations
Apricot jam showed cytotoxic effects in healthy cells at high concentrations (>400 µg/mL)
Aqueous extract of apricot fruit exhibited a concentration-dependent cytotoxic effect in cancer cells
64.60% and 58.8% cytotoxicity were noted in Hep-3B cells at 800 and 1600 µg/mL respectively
Jam promoted cancer cell proliferation at higher concentrations, contrary to the fruit extract
Aqueous extract demonstrated superior antioxidant effects compared to jam.

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Comparative evaluation shows apricot fruit reduces cancer cell growth, while jam may promote it, highlighting dietary impacts.

Güven et al. (2026) studied this question.

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