Aligning Test and Reference Methods by Simultaneous Correction of Proportional and Constant Bias in Comparative Analysis

Jesse A. Canchola; Benjamin Blue La Brot; Daniel Jarem; Sonia Rao

doi:10.1093/jalm/jfag025

February 10, 2026The Journal of Applied Laboratory MedicineOpen Access

Aligning Test and Reference Methods by Simultaneous Correction of Proportional and Constant Bias in Comparative Analysis

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Key Points

The aim is to enhance the reliability of comparative studies by correcting both proportional and constant biases.
Develop a unified correction technique.
Conduct comparative analysis across various diagnostic platforms.
Implement simultaneous correction of biases for accurate recalibration.
Improved reliability in comparative studies.
Establishment of a reproducible method for recalibration.
Demonstrated efficacy across multiple diagnostic platforms.

Implication

Unified correction enhances reliability in comparative analysis, suggesting improved calibration across platforms.

Abstract

This unified correction enhances reliability in comparative studies and provides a reproducible foundation for recalibration across diagnostic platforms.

Discussion

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Cite This Study

Canchola et al. (2026) studied this question.

synapsesocial.com/papers/69a7ccb2d48f933b5eed878f https://doi.org/10.1093/jalm/jfag025

View Full Paper

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Aligning Test and Reference Methods by Simultaneous Correction of Proportional and Constant Bias in Comparative Analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

Aligning Test and Reference Methods by Simultaneous Correction of Proportional and Constant Bias in Comparative Analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

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