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March 4, 2026The Journal of Rheumatology0 citationsOpen Access

Osteolysis After Interphalangeal Joint Arthrodesis in Systemic Sclerosis: A Case Series

KMKristen R. MathiasJGJheneale Renee GrandisonSLScott D. Lifchez

Key Points

  • To investigate the occurrence of osteolysis following interphalangeal joint arthrodesis in patients with systemic sclerosis.
  • Case series of patients undergoing interphalangeal joint arthrodesis
  • Assessment of post-surgical outcomes related to osteolysis
  • Analysis of functional impairment and deformity post-procedure
  • Observations of significant osteolysis in distal phalanges post-surgery
  • Incidence of marked deformity in patients after joint arthrodesis
  • Correlation noted between surgery and functional impairment in some cases

Abstract

Acro-osteolysis (AO), defined as osseous resorption mainly occurring in the distal phalanges of the fingers and toes, is a well-recognized complication of systemic sclerosis (SSc) that can lead to marked deformity and functional impairment.1 Interphalangeal joint arthrodesis is a surgical option for SSc patients with severe hand deformities that cause pain, functional impairment, and/or pressure ulceration refractory to medical management.2

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Cite This Study

Mathias et al. (2026) studied this question.

synapsesocial.com/papers/69a7cd1dd48f933b5eed92d5https://doi.org/10.3899/jrheum.2025-1292
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