Key result
Lobectomy uncovers incidental diffuse pulmonary meningiotheliomatosis alongside lung adenocarcinoma.
Why the study?
Diffuse pulmonary meningiotheliomatosis and minute pulmonary menigiothelial-like nodules are rare benign pulmonary pathologies that should be considered in the differential diagnosis of pulmonary nodules.
Diffuse pulmonary meningotheliomatosis is a rare, often benign incidental finding that should be considered in the differential diagnosis of pulmonary nodules.
Should be considered in differential of pulmonary nodules; extends literature on its coexistence with lung adenocarcinoma.
Diffuse pulmonary meningiotheliomatosis (DPM) and minute pulmonary menigiothelial-like nodules (MPMNs) are rare pulmonary pathologies often detected incidentally. These lesions are often benign. However, they should be considered in the differential diagnosis of pulmonary nodules. Immunohistochemical analysis established their meningothelial origin with positive reactivity to markers ubiquitously expressed in meningiomas. We present a case of a female in her late 70s who underwent lobectomy for suspected non-small cell lung cancer. Pathological assessment revealed adenocarcinoma with background of DPM. The paucity of literature warrants careful assessment and workup of these cases to exclude underlying sinister findings.
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Hemead et al. (2026) studied this question. Diffuse pulmonary meningiotheliomatosis was incidentally found alongside lung adenocarcinoma in a lobectomy specimen, highlighting the need for careful differential diagnosis.
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