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March 4, 2026Antibiotics0 citationsOpen Access

Bridging the Evidence-to-Policy Gap: Strengthening Capacities in Low- and Middle-Income Countries to Translate Antimicrobial Resistance Data and Evidence into Effective Policies

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PPPrerana ParajuleeInternational Vaccine InstituteSGSajan GunarathanaABAnthony John BurnettInternational Vaccine Institute

Key Points

  • This research aims to strengthen capacities in low- and middle-income countries for effective AMR policy-making using data and evidence.
  • Implemented a structured, hybrid E2P capacity-strengthening model across four countries.
  • Combined online and in-person training, targeted mentorship, and policy engagement.
  • Developed country-specific evidence briefs for policy and conducted policy dialogues.
  • Participants reported increased confidence and capability in using AMR evidence for policy.
  • Identified persistent constraints such as sectoral silos and gaps in evidence-use systems.
  • Enhanced cross-sectoral collaboration and a clearer process for developing evidence-based policies.

Abstract

Background: The translation of antimicrobial resistance (AMR) data and evidence into policy remains limited in many low- and middle-income countries (LMICs) in Asia and Africa, despite expanded investments being made in AMR surveillance and research. This is due to fragmented governance, weak knowledge translation capacity, and insufficient Results: Participant surveys showed improved confidence and capability to synthesize, interpret, and apply AMR evidence to inform policy. The four countries highlighted persistent constraints such as sectoral silos, limited institutional ownership, and gaps in evidence-use systems, but reported enhanced cross-sectoral collaboration and a clearer, replicable process for EBP development. Methodology: During Phase II of the Fleming Fund-resourced Regional AMR Data Analysis for Advocacy, Response, and Policy (RADAAR) project, a structured, hybrid, evidence-to-policy (E2P) capacity-strengthening model was implemented in Bhutan, Ghana, Kenya, and Lao People’s Democratic Republic, combining online and in-person training, targeted mentorship, and policy engagement. Each country developed a country-specific evidence brief for policy (EBP) and conducted policy dialogues to facilitate stronger decision maker involvement. Conclusions: RADAAR’s approach strengthened the foundational capacity for evidence-informed policymaking and demonstrated the value of institutionalized knowledge translation mechanisms. Sustained investment in E2P systems is essential to bridge the AMR E2P gap and ultimately support AMR prevention and control.

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Cite This Study

Parajulee et al. (2026) studied this question.

synapsesocial.com/papers/69a7cd5ed48f933b5eed99f1https://doi.org/10.3390/antibiotics15030255
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