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March 5, 2026Organic & Biomolecular Chemistry0 citationsOpen Access

Facile one-pot synthesis of 5-alkylidene-2,3,5,6,7,8-hexahydroimidazo1,2-apyridines

EYEsra Korkmaz YurtoğluMZMetin Zora

Key Points

  • The study aims to develop a simple and efficient one-pot method for synthesizing 5-alkylidene-2,3,5,6,7,8-hexahydroimidazo[1,2-a]pyridines.
  • Utilized a one-pot reaction approach.
  • Refluxed a mixture of bis-α,β-alkynic ketones with ethylenediamine in dioxane.
  • Focused on the generation of specific chemical compounds.
  • Successful formation of 5-alkylidene-2,3,5,6,7,8-hexahydroimidazo[1,2-a]pyridines.
  • Demonstrated efficiency of the one-pot protocol.
  • Provided a new method for generating complex organic compounds.

Abstract

A straightforward and efficient one-pot protocol for the synthesis of 5-alkylidene-2,3,5,6,7,8-hexahydroimidazo1,2-apyridines is reported. When subjected to the reaction with ethylenediamine in refluxing dioxane, bis-α,β-alkynic ketones, i.e. 1,9-diarylnona-2,7-diyne-1,9-diones, afford 5-alkylidene-2,3,5,6,7,8-hexahydroimidazo1,2-apyridines. Generation...

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Cite This Study

Yurtoğlu et al. (2025) studied this question.

synapsesocial.com/papers/69a91d8dd6127c7a504c074bhttps://doi.org/10.1039/d5ob01892g
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