What question did this study set out to answer?

The study aims to assess the impact of an Antimicrobial Stewardship Program on antibiotic use and bacterial resistance in a hospital setting.

March 5, 2026AntibioticsOpen Access

Impact of an Antimicrobial Stewardship Program on Antibiotic Consumption, Bacterial Susceptibility, and Costs in a High-Complexity Public Hospital

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Quasi-experimental study evaluates antibiotic consumption in a hospital, indicating reduced usage and costs after an intervention.

The study aims to assess the impact of an Antimicrobial Stewardship Program on antibiotic use and bacterial resistance in a hospital setting.
Conducted a quasi-experimental pre–post study
Used interrupted time-series design in an adult ICU
Measured antimicrobial consumption and susceptibility
Analyzed data using Joinpoint regression and statistical tests.
Significant reductions in antibiotic consumption for all agents except polymyxin B
Improved susceptibility among key Gram-negative pathogens post-intervention
Annual antimicrobial costs decreased by approximately USD 174,000

Andrade et al. (2026) studied this question.

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