Demonstrates a novel framework that enhances ADHD classification accuracy by integrating static and dynamic brain connectivity features.
The diagnosis of attention-deficit/hyperactivity disorder (ADHD) has long relied on subjective scales, lacking objective neuroimaging biomarkers. Static functional connectivity (sFC) and dynamic functional connectivity (dFC), as commonly used metrics in resting-state functional magnetic resonance imaging (rs-fMRI) analysis, provide important perspectives for related research. However, existing unimodal approaches struggle to effectively integrate the spatiotemporal characteristics of functional connectivity. To address this, this paper proposes the multimodal fusion framework D-SFANet, which synergistically models the static and dynamic features of brain functional connectivity through an attention mechanism: in the static path, it integrates a multi-scale convolutional network with phenotypic information extraction to extract hierarchical topological features; in the dynamic path, it combines graph theory with a bidirectional long short-term memory network (BiLSTM) to capture key state transition patterns in brain networks. Experimental validation demonstrates that D-SFANet achieves significantly higher classification accuracy than existing mainstream methods, robustly validating the effectiveness of its spatiotemporal fusion strategy.
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Zhang et al. (2026) studied this question.
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