Global Prevalence of Adherence to Gluten-Free Diet in Patients with Celiac Disease: A Systematic Review and Meta-analysis

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Key Points

To assess the adherence levels to gluten-free diet among patients with celiac disease globally.
Conducted a systematic review of existing studies on gluten-free diet adherence.
Performed a meta-analysis to aggregate data on compliance rates across different populations.
Analyzed factors affecting adherence to the gluten-free diet.
Approximately one in three celiac disease patients struggles to adhere to the gluten-free diet.
Identified key factors influencing adherence, including education and support.
Highlighted the necessity for strategic interventions to improve diet compliance.

Systematic review reveals low adherence to gluten-free diet in celiac disease patients, suggesting a need for better strategies.

One in three patients with CeD is unable to maintain a good adherence to GFD. There is need to develop strategies to improve the adherence to GFD.

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Mehta et al. (2026) studied this question.

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