What question did this study set out to answer?

The review aims to explore immunometabolic changes in sepsis and their relationship to multiple organ dysfunction.

Immunometabolic Reprogramming in Experimental Sepsis: A Driver of Multiple Organ Dysfunction Syndrome

View Full Paper

Ask AI

Bookmark

Authors

A review explores how immunometabolic changes drive organ dysfunction in experimental sepsis, suggesting new therapeutic approaches.

The review aims to explore immunometabolic changes in sepsis and their relationship to multiple organ dysfunction.
Systematic overview of metabolic alterations in immune cells and organs in experimental sepsis models.
Examination of key features like glycolysis, mitochondrial function, and lipid metabolism.
Assessment of organ-specific metabolic dysfunctions and potential therapeutic targets.
Enhanced glycolysis is associated with organ damage in sepsis models.
Impairment of mitochondrial function contributes to immune cell dysregulation.
Disturbances in lipid metabolism are linked to the progression of multiple organ dysfunction syndrome.

Wu et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark