What question did this study set out to answer?

The aim is to understand how thyroxine, thiourea, and thyroid-releasing factor affect the cephalic lobe of the hypophysis in chick embryos.

March 6, 2026Open Access

An ultrastructural study of the cephalic lobe of the hypophysis in chick embryos treated with thyroxine, thiourea and thyroid-releasing factor

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Reveals changes in cell types and granule secretion in chick embryos following hormone treatments.

The aim is to understand how thyroxine, thiourea, and thyroid-releasing factor affect the cephalic lobe of the hypophysis in chick embryos.
Administered thyroxine, thiourea, and T.R.F. to chick embryos on incubation day 5.
Performed ultrastructural analysis of the cephalic lobe on incubation days 8, 10, 12, 14, and 16.
Identified various cell types present in the hypophysis at different incubation stages.
Increased cytoplasmic granules observed in Type III thyrotrope on incubation day 8.
Thyrotrope granules significantly increased following treatments on days 10, 12, 14, and 16.
Decrease in granules in all cell types on incubation day 12 after T.R.F. administration.

Marlene Dawn Henry (1978) studied this question.

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