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March 6, 2026The Egyptian Journal of Neurology Psychiatry and Neurosurgery0 citationsOpen Access

Indications for Cerebrospinal Fluid Diversion After Pediatric Brain Tumor Surgery

Establishing the indications of cerebrospinal fluid diversion following pediatric primary intracranial tumor resection: a systematic review and meta-analysis

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Authors

BLBryan De LiyisKWKadek Dede Frisky WiyanjanaNGNyoman Golden

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Overview

Systematic review analyzes factors influencing cerebrospinal fluid diversion in children post-tumor resection, suggesting key indicators.

Key Points

  • The study aims to identify evidence-based indicators for cerebrospinal fluid diversion in children after tumor resection.
  • Conducted systematic searches in ScienceDirect, Medline, and Cochrane databases.
  • Included longitudinal studies up to April 2024.
  • Analyzed risk factors based on preoperative, surgical, tumor, and postoperative parameters.
  • Performed subgroup analysis based on ethnicity, tumor location, and presence of hydrocephalus.
  • Found preoperative hydrocephalus and periventricular lucency were linked to higher CSF diversion risk.
  • Identified medulloblastoma and postoperative intraventricular blood as significant risk factors.
  • Ventricle infiltration and large tumor volume also increased likelihood of CSF diversion.
  • Subgroup analysis showed infection risk amplifies in children without hydrocephalus.

Cite This Study

Liyis et al. (2026) studied this question.

synapsesocial.com/papers/69aa7066531e4c4a9ff5a24fhttps://doi.org/10.1186/s41983-026-01087-3
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Risk factors for postoperative ventriculoperitoneal shunt requirement in pediatric patients with brain tumors invading or adjacent to CSF circulation pathways2024 · 3 citations
  2. 2Hydrocephalus following Brain Tumor Surgery: Factors Correlating with Occurrence of Postoperative Hydrocephalus and Predictive Scoring Model2024 · 8 citations
  3. 3An Analysis of Factors Determining the Need for Ventriculoperitoneal Shunts after Posterior Fossa Tumor Surgery in Children1994 · 19 citations
  4. 4Registration of systematic reviews in PROSPERO: 30,000 records and counting2018 · 518 citations
  5. 5Effects of increased intracranial pressure on cerebrospinal fluid influx, cerebral vascular hemodynamic indexes, and cerebrospinal fluid lymphatic efflux2022 · 55 citations