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This research aims to investigate how malathion affects the development of yolk sac endoderm in chick embryos.

March 6, 2026Open Access

The effects of malathion on the development of the yolk sac endoderm in the chick embryo

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Research shows malathion exposure inhibits metabolism in chick embryos, suggesting developmental risks.

This research aims to investigate how malathion affects the development of yolk sac endoderm in chick embryos.
Exposed chick embryos to a teratogenic dose of malathion on the 5th day of incubation.
Studied effects on yolk sac development and related metabolic processes.
Analyzed changes in carbohydrate and lipid metabolism, hemopoietic tissue, RNA content, and lysosomal activity.
Malathion inhibited carbohydrate metabolism in the yolk sac.
Lipid metabolism was also significantly inhibited.
There were decreases in hemopoietic tissue and the number of acidophilic protein granules.
Notable reductions in RNA content and lysosomal activity were observed.

Tanya Patricia Acorn (1976) studied this question.

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