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March 6, 2026Turkiye Klinikleri Journal of Case Reports0 citationsOpen Access

Management of Persistent Pupillary Membrane Presenting with Strabismus

MBMustafa BÜLBÜLMEMurat Erdağ

Key Points

  • This report aims to illustrate the visual impairments caused by persistent pupillary membrane in children and emphasize the importance of early intervention.
  • Case report of a 4-year-old male with persistent pupillary membrane corrected for visual issues.
  • Detailed ophthalmologic evaluation conducted to assess visual impairment and misalignment.
  • Analysis of the impact of persistent pupillary membranes on visual development and amblyopia.
  • Patient developed deprivation amblyopia due to obstructed visual axis from persistent pupillary membrane.
  • Esotropia was identified as a result of visual deprivation.
  • Timely intervention was suggested as essential to prevent long-term visual complications.

Abstract

In this study, we report a case of a 4-year-old male patient who presented with persistent pupillary membrane (PPM) in the right eye, accompanied by secondary deprivation amblyopia and esotropia. PPM is a congenital ocular anomaly resulting from remnants of the anterior tunica vasculosa lentis. While these membranes typically regress spontaneously within the first year of life, persistent cases may obstruct the visual axis and cause significant visual problems. If left untreated, PPM can lead to various types of amblyopia, including deprivation, strabismic, or anisometropic amblyopia. In our patient, the persistent membrane resulted in visual deprivation, contributing to the development of amblyopia and ocular misalignment. Early diagnosis and intervention are crucial to prevent long-term visual impairment in similar cases. This report aims to highlight the importance of careful ophthalmologic evaluation in infants with PPM to ensure timely management and prevent amblyogenic effects.

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Cite This Study

BÜLBÜL et al. (2026) studied this question.

synapsesocial.com/papers/69aa7077531e4c4a9ff5a4b4https://doi.org/10.5336/caserep.2025-113203
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