Enhanced detection of high-risk human papillomavirus by in situ hybridization with expansion from 7 to 18 genotypes in anal biopsies

Puntos clave

• The aim is to assess the impact of expanding the in situ hybridization (ISH) panel on detecting high-risk HPV genotypes in anal biopsies.
• Expanded ISH panel from 7 to 18 genotypes
• Conducted analysis on anal biopsies
• Identified presence of high-risk HPV in both HSIL and non-HSIL cases
• Improved detection rates of high-risk HPV in anal HSIL cases
• Identified additional high-risk HPV cases in patients without HSIL