A systematic review finds tenecteplase effective for reperfusion in basilar artery occlusion, suggesting it as a viable alternative to alteplase.
In BAO, tenecteplase as bridging therapy prior to EVT improves early and final reperfusion without increasing hemorrhagic risk or mortality, with functional outcomes comparable to alteplase, although the current evidence is limited.
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Fernandes et al. (2026) studied this question.
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