Accelerated TMS with the H1-coil for Depression: A Multisite, Randomized Non-Inferiority Trial | Synapse
March 7, 2026Open Access
Accelerated TMS with the H1-coil for Depression: A Multisite, Randomized Non-Inferiority Trial
Key Points
To compare the effectiveness of accelerated TMS with the H1-coil against standard HF TMS for treating depression.
Conducted a multisite, randomized, non-inferiority trial
Participants received either accelerated TMS or standard HF TMS
Measured outcomes focused on remission rates and treatment tolerability
Accelerated TMS shows outcomes comparable to standard HF TMS
Both treatment methods proved safe and well-tolerated
Faster remission observed with accelerated TMS
Abstract
ACC-iTBS TMS with the H1 coil is a safe, well-tolerated, and time-efficient alternative to standard HF H1-coil TMS, offering comparable outcomes and faster remission.