Accelerated TMS with the H1-coil for Depression: A Multisite, Randomized Non-Inferiority Trial

Q: What does this research mean for the field?

ACC-iTBS TMS with the H1 coil is a safe and time-efficient alternative to standard HF H1-coil TMS, providing comparable outcomes and faster remission in patients with depression. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

Colleen A. Hanlon; Yiftach Roth; Richard A. Bermudes; Eliza Brink; Molly Davis; Dawn DeBrocco; Shelli Ellis; Lindsey Jones; Aftab Khan; Carlene McMillan; Aswin Kumar Mudunuru; Owen S. Muir; Gabriel S. Pell; Timothy Prestley; M.S. Reddy; Adi Rachelson; Elyssa Sisko; Samson Seplow; Natanya Slomowitz; Ahava Stein; Daniel B. Thistlethwaite; Russ Voltin; Aron Tendler

doi:10.1016/j.brs.2026.103050

Key Points

To compare the effectiveness of accelerated TMS with the H1-coil against standard HF TMS for treating depression.
Conducted a multisite, randomized, non-inferiority trial
Participants received either accelerated TMS or standard HF TMS
Measured outcomes focused on remission rates and treatment tolerability
Accelerated TMS shows outcomes comparable to standard HF TMS
Both treatment methods proved safe and well-tolerated
Faster remission observed with accelerated TMS

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Implication

Multisite trial compares accelerated TMS with standard TMS in depression, suggesting effective alternatives.

Abstract

ACC-iTBS TMS with the H1 coil is a safe, well-tolerated, and time-efficient alternative to standard HF H1-coil TMS, offering comparable outcomes and faster remission.

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Cite This Study

Hanlon et al. (2026) studied this question.

synapsesocial.com/papers/69abc0925af8044f7a4e93bb https://doi.org/10.1016/j.brs.2026.103050

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Accelerated TMS with the H1-coil for Depression: A Multisite, Randomized Non-Inferiority Trial

Key Points

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Implication

Abstract

Discussion

Cite This Study

Accelerated TMS with the H1-coil for Depression: A Multisite, Randomized Non-Inferiority Trial

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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