Ultrasound-guided lymph node biopsies: feasible and safe use of pathology services in a resource-limited, high TB/HIV prevalence setting

Tapiwa Kumwenda; Veronica Phiri; Kelvin Rambik; Dr Bianca Sossen; Bal Mukunda; George Y Fedoriw; Mathews S. Painschab; Ethel Rambiki; Claudia Wallrauch; Tom Heller

doi:10.5826/tuj.2026.18321

March 4, 2026The Ultrasound JournalOpen Access

Ultrasound-guided lymph node biopsies: feasible and safe use of pathology services in a resource-limited, high TB/HIV prevalence setting

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Key Points

The study aims to evaluate the feasibility and safety of ultrasound-guided core needle biopsies (CNB) for lymph nodes in a high TB/HIV prevalence area.
Investigated the use of ultrasound-guided CNB in routine ART clinics.
Analyzed patients with enlarged peripheral lymph nodes after negative Xpert-Ultra fine needle aspiration (FNA).
Conducted abdominal ultrasounds to identify spleen lesions and other findings.
Ultrasound-guided CNB is shown to be a safe and effective procedure.
Hematological malignancies were frequently diagnosed after negative FNA results.
Abnormal abdominal ultrasound findings and hypoechoic spleen lesions were common in patients with hematological issues.

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Implication

Demonstrates the safe use of ultrasound-guided biopsies in ART clinics, indicating potential improvements in patient management in resource-limited settings.

Abstract

Ultrasound-guided CNB of enlarged peripheral LN is a safe, effective addition to routine ART clinics. After negative Xpert-Ultra FNA, hematological malignancies were common. Abdominal ultrasound findings were frequently abnormal overall and hypoechoic spleen lesions were more common in patients with hematological abnormalities.

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Kumwenda et al. (2026) studied this question.

synapsesocial.com/papers/69abc0de5af8044f7a4e98b9 https://doi.org/10.5826/tuj.2026.18321

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Ultrasound-guided lymph node biopsies: feasible and safe use of pathology services in a resource-limited, high TB/HIV prevalence setting

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Ultrasound-guided lymph node biopsies: feasible and safe use of pathology services in a resource-limited, high TB/HIV prevalence setting

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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