What question did this study set out to answer?

To explore the interactions between folate supplementation, MTHFR genetics, and vitamin B12 levels on various pregnancy outcomes.

March 7, 2026SHILAP Revista de lepidopterologíaOpen Access

The roles of folate, MTHFR genetics, vitamin B12 in pregnancy outcomes

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To explore the interactions between folate supplementation, MTHFR genetics, and vitamin B12 levels on various pregnancy outcomes.
Review existing literature on folate supplementation and pregnancy outcomes.
Evaluate the influence of MTHFR genetic polymorphisms on folate metabolism.
Analyze the relationship between vitamin B12 levels and pregnancy outcomes.
Folate supplementation is crucial for preventing neural tube defects but shows inconsistent effects on other outcomes.
MTHFR genetic polymorphisms significantly influence individual responses to folate supplementation.
No optimal folate level determined for preventing various adverse pregnancy outcomes.

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Implication

This review investigates the impact of folate, MTHFR genetics, and vitamin B12 on pregnancy outcomes, suggesting a need for personalized nutrition strategies.

Cite This Study

Yang et al. (2026) studied this question.

synapsesocial.com/papers/69abc1015af8044f7a4e9a52 https://doi.org/10.3389/fnut.2026.1785263

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Implication

This review investigates the impact of folate, MTHFR genetics, and vitamin B12 on pregnancy outcomes, suggesting a need for personalized nutrition strategies.

The roles of folate, MTHFR genetics, vitamin B12 in pregnancy outcomes

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Discussion

Implication

Cite This Study

The roles of folate, MTHFR genetics, vitamin B12 in pregnancy outcomes

Key Points

Discussion

Implication

Cite This Study

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