Sustained symptom relief and safety over five years following a single intra-articular injection of 2.5% polyacrylamide hydrogel in patients with knee osteoarthritis

Key Points

• To evaluate the long-term efficacy and safety of a single intra-articular injection of polyacrylamide hydrogel in knee osteoarthritis.
• Conducted an observational study over five years
• Administered a single intra-articular injection of 2.5% polyacrylamide hydrogel
• Monitored pain and functional outcomes at regular intervals
• Sustained improvements in pain levels reported over five years
• Enhanced function observed among participants throughout the study period
• Favorable safety profile maintained without significant adverse effects