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March 7, 2026Frontiers in PsychiatryOpen Access

Nutritional status mediates the relationship between depression and mild cognitive impairment among Chinese community-dwelling older adults

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Authors

XCXiaoyu ChenPHPeipei HanZLZhenwen Liang

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Overview

Our study reveals nutritional status mediates cognitive decline in older adults with depression, suggesting potential interventions.

Key Points

  • The study aims to explore how nutritional status mediates the relationship between depression and mild cognitive impairment among older adults.
  • Included 4799 community-dwelling Chinese older adults aged 60+.
  • Used the Geriatric Depression Scale to assess depression severity.
  • Evaluated nutritional status with the Mini Nutritional Assessment-Short Form.
  • Assessed cognitive function using the Mini-Mental State Examination.
  • Conducted logistic regression and mediation analyses.
  • 11.8% of older adults exhibited depression, while 12.1% had MCI.
  • 18.8% were at risk of malnutrition, and 1% were malnourished.
  • Risk of malnutrition or depression was linked to MCI.
  • Nutritional status significantly mediated the relationship between depression and cognitive function.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/69abc1235af8044f7a4e9cf3https://doi.org/10.3389/fpsyt.2026.1684063
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nutritional status mediates the relationship between depression and mild cognitive impairment among Chinese community-dwelling older adults2024
  2. 2Cross-sectional study of the association between nutrition and depression in older people living in nursing homes2025 · 3 citations
  3. 3The Association of Cognitive Impairment and Depression with Malnutrition among Vulnerable, Community-Dwelling Older Adults: A Large Cross-Sectional Study2024 · 9 citations
  4. 4The Effects of Nutrition on Depression in Older Adults Living in Nursing Homes: A Dilemma or a Vicious Circle?2024
  5. 5Prevalence of mild cognitive impairment and its association with malnutrition in older Chinese adults in the community2024 · 16 citations