What question did this study set out to answer?

This research aimed to assess trends in healthcare-associated infection rates among preterm infants in Germany over 15 years.

March 7, 2026Open Access

Decrease in healthcare-associated infection rates in preterm infants—longitudinal data from 15 years of nationwide surveillance in Germany

FRFerenc Darius RuetherLaboratoire National de Référence CTC Triay GKGizem KaradağHumboldt-Universität zu Berlin

Key Points

This research aimed to assess trends in healthcare-associated infection rates among preterm infants in Germany over 15 years.
Utilized nationwide surveillance data from NEO-KISS from 2008 to 2022.
Monitored incidence densities of healthcare-associated infections, including HAS, HAP, and NEC.
Analyzed longitudinal data to identify trends over the specified period.
Demonstrated a decrease in incidence densities of healthcare-associated infections.
Notable reductions observed in categories including HAS (healthcare-associated sepsis), HAP (hospital-acquired pneumonia), and NEC (necrotizing enterocolitis).

Abstract

In Germany, the surveillance data for neonates in NEO-KISS between 2008 and 2022 showed a nationwide decrease in incidence densities of HAS, HAP, and NEC. The continuous engagement with NEO-KISS surveillance data may have contributed to this reduction.

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