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This report reveals fluconazole resistance in Candida parapsilosis isolates, suggesting emerging antifungal challenges in Brazil.
This is the first report of fluconazole-resistant C. parapsilosis sensu stricto isolates harbouring the G458S ERG11p substitution in Brazil. Here reported isolates showed resistance to fluconazole alone, which is an unusual pattern among C. parapsilosis sensu stricto isolates harbouring the G458S substitution.
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Gonçalves et al. (2026) studied this question.
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