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The research aims to describe cancer incidence and mortality trends among adults aged 65 and older in the U.S.

March 7, 2026npj AgingOpen Access

Cancer incidence and mortality trends among older adults

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Epidemiological analysis reports cancer incidence and mortality trends in older adults, suggesting evolving patterns over time.

The research aims to describe cancer incidence and mortality trends among adults aged 65 and older in the U.S.
Analyzed cancer data from the Surveillance, Epidemiology, and End Results database from 1975 to 2019.
Calculated average annual percent change (AAPC) using joinpoint regression modeling.
Examined trends across different cancer subtypes and genders.
Cancer incidence in older adults increased by an AAPC of 0.250 (P < 0.001).
Melanoma saw the highest increases in incidence, especially in males (AAPC 4.887).
Cancer mortality showed a decrease with an AAPC of -0.317 (P < 0.001).
Significant declines in mortality occurred in stomach cancer for both genders and colon cancer.
Lung cancer mortality increased among females, and liver cancer mortality increased among males.

Morse et al. (2026) studied this question.

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