Reveals how desmoplastic stromal reaction influences lymph node surgery decisions in medullary thyroid carcinoma, suggesting improved precision in treatment.
DSR negativity reliably identifies an indolent subgroup with negligible metastatic risk, whereas increasing desmoplasia stratifies patients into higher-risk categories. The incorporation of DSR alongside established biomarkers such as Ctn may refine surgical decision-making and may help tailor the extent of LN dissection in sporadic MTC.
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Özel et al. (2026) studied this question.
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