Key result
Radical surgery combined with adjuvant or neoadjuvant chemotherapy yields the best outcomes in the management of desmoplastic small round cell tumor.
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Desmoplastic Small Round Cell Tumor (DSRCT) is a rare and an aggressive malignancy with poor outcome. This tumor can co-express epithelial, neural, and mesenchymal markers. The molecular hallmark of DSRCT is the EWS-WT1 fusion protein. Despite the diversities in treatment modality, the best results have been seen with radical surgery and adjuvant or neoadjuvant chemotherapy.
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Radical surgery combined with adjuvant or neoadjuvant chemotherapy provides the best outcomes for patients with desmoplastic small round cell tumor.
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Kallianpur et al. (2012) studied this question. Radical surgery combined with adjuvant or neoadjuvant chemotherapy yields the best outcomes in the management of desmoplastic small round cell tumor.
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