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March 7, 2026OTA International The Open Access Journal of Orthopaedic TraumaOpen Access

Intramedullary nailing with absorbable antibiotic-eluting ceramic for fracture-related infection prophylaxis in high-risk open fractures: a case series and technique

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Authors

SSScott M. SandilandsBaptist Hospital of MiamiADAkshay V. DajiJohn F. Kennedy Medical Center

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Implication

Case series demonstrates effective fracture-related infection prophylaxis in high-risk open fractures, suggesting new intervention opportunities.

Key Points

  • The study aims to evaluate a novel technique for preventing fracture-related infections in open fractures using local antibiotic delivery.
  • Nine patients with high-risk open fractures underwent intramedullary nailing with Cerament G augmentation.
  • Patients presented with Gustilo–Anderson Type II to IIIC open fractures involving the tibia, femur, or humerus.
  • Postoperative outcomes measured included fracture-related infection incidence, union, complications, and functional recovery.
  • All fractures achieved union at a mean follow-up of 9.1 months with zero cases of fracture-related infection.
  • Two cases required flap coverage, with one flap failure successfully revised.
  • There were no secondary procedures for infection or implant removal, and serous drainage resolved within one week.

Cite This Study

Sandilands et al. (2026) studied this question.

synapsesocial.com/papers/69abc2175af8044f7a4eb533https://doi.org/10.1097/oi9.0000000000000478
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