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March 7, 2026Obstetric Anesthesia Digest

Weighing Up Causes of and Risk Factors for Postpartum Haemorrhage to Improve its Prevention

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Authors

ADA-S Ducloy-BouthorsHôpital Jeanne de FlandreMVM-F E VidarteHôpital Jeanne de Flandre

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Overview

The E-MOTIVE trial demonstrates improved postpartum hemorrhage management in a large cohort, suggesting effective interventions for at-risk women.

Key Points

  • The aim is to identify risk factors and improve prevention strategies for postpartum hemorrhage.
  • Conducted the E-MOTIVE trial in 80 hospitals across four countries.
  • Involved over 210,000 patients to assess PPH management.
  • Used calibrated blood collection drapes for accurate blood loss measurement.
  • Triggered bundled first-response treatments upon detection of 300 mL blood loss.
  • Reduced severe PPH events from 4.3% in standard care to 1.6% in the intervention group.
  • Significantly lowered the need for rescue laparotomy and mortality.
  • Highlighted the effectiveness of structured early response to bleeding.

Cite This Study

Ducloy-Bouthors et al. (2026) studied this question.

synapsesocial.com/papers/69abc2175af8044f7a4eb607https://doi.org/10.1097/01.aoa.0001178700.80252.6b
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical care processes for early postpartum haemorrhage diagnosis: a nested observational study within the E-MOTIVE trial2025
  2. 2A cost-effectiveness analysis of early detection and bundled treatment of postpartum hemorrhage alongside the E-MOTIVE trial2024 · 20 citations
  3. 3Blood loss monitoring chart, a game changer in postpartum hemorrhage detection and treatment: A direct observation study in 7 E-MOTIVE trial hospitals in Kenya2024 · 1 citations
  4. 4Postpartum Hemorrhage: A Diagnostic and Therapeutic Challenge2024
  5. 5<scp>FIGO</scp> recommendations on objective measurement of blood loss after birth for early detection of postpartum hemorrhage2025 · 13 citations