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March 7, 2026Kirkuk journal of scienceOpen Access

Impacts of Moringa oleifera Seed Nanoparticles on Growth, Serum Biochemistry, and Hepatic Enzymes in Diet-Induced Hyperlipidemic Male Wistar Rats

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Authors

MNMuhammad NaeemGovernment College University, LahoreHMHusni MhammadUniversity of DuhokAAAhmed AhmedAkita University

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Overview

Examines how Moringa oleifera seed nanoparticles enhance health in hyperlipidemic male Wistar rats, suggesting therapeutic benefits.

Key Points

  • The aim is to evaluate the protective effects of Moringa oleifera seed nanoparticles on hyperlipidemia-related parameters in male Wistar rats.
  • Conducted on male Wistar rats divided into five groups: normal control, high-fat diet control, and three high-fat diet groups treated with different doses of MOS-NPs.
  • Administered MOS-NPs at 25, 100, and 200 mg/kg BW/day for 60 days.
  • Measured parameters included body weight, fat percentage, liver weight, and serum biochemistry.
  • High-fat diet control rats showed significant increases in body weight gain, epididymal fat percentage, and liver weight.
  • MOS-NPs reversed these negative effects, especially at the highest dose of 200 mg/kg, returning parameters close to normal levels.
  • The dose of 200 mg/kg significantly improved hepatic enzyme levels (ALT, AST) and serum biochemical markers.

Cite This Study

Naeem et al. (2026) studied this question.

synapsesocial.com/papers/69abc2355af8044f7a4eb977https://doi.org/10.32894/kujss.2026.168009.1269
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Protective role of Moringa oleifera seed nanoparticles against lipid metabolism disturbances, oxidative stress, and immune dysregulation in diet-induced hyperlipidemic Wistar rats2026
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  3. 3An Evaluation of Anti-hyperlipidemic Activity of Ethanolic Extract of Moringa oleifera on High Fat Induced Hyperlipidemic Rat Model2024 · 2 citations
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