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March 7, 2026Asian Journal of Organic Chemistry

Electrochemical Regioselective C(sp 2 )–H Selenylation of Pyrrolo2,3‐ d pyrimidine Derivatives With Diselenides

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Authors

ZLZixuan LiuJTJiaqi TongBLBin Liu

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Overview

Electrochemical approach demonstrates effective selenylation of compounds, indicating broad application potential.

Key Points

  • The research aims to establish an efficient electrochemical method for selenylation of pyrrolo[2,3-d]pyrimidine derivatives.
  • Utilized diselenides as the selenium source for selenylation.
  • Performed reactions under catalyst- and oxidant-free conditions.
  • Conducted preliminary mechanistic studies to investigate reaction intermediates.
  • Achieved efficient formation of C(sp2)–Se bonds.
  • Demonstrated broad substrate scope and good functional group compatibility.
  • Highlighted high site-selectivity and exceptional atom economy.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69abc2615af8044f7a4ebf13https://doi.org/10.1002/ajoc.70343
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