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March 7, 2026Open Access

Quality of Life of Patients After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Systematic Review

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Authors

MRMSc Noskova Irina RNDPDaphne Kaitelidou, MSc, PhDPPPetros Galanis, MSc, PhD

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Overview

Systematic review finds cytoreductive surgery and HIPEC impact quality of life in patients, suggesting the need for optimized care.

Key Points

  • Evaluate the impact of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy on patients' quality of life.
  • Conducted a systematic review following PRISMA guidelines and PICO method.
  • Identified studies published after 2014 using multiple academic databases.
  • Analyzed 29 studies that utilized validated quality of life assessment tools.
  • Quality of life declines in the first 3 months post-surgery but improves by 6-12 months.
  • Common QoL assessment tools included EORTC QLQ-C30, SF-36, and FACT-C.
  • Factors influencing QoL include age, gender, baseline health, completeness of cytoreduction, and postoperative complications.

Cite This Study

RN et al. (2026) studied this question.

synapsesocial.com/papers/69abc2855af8044f7a4ec2c3https://doi.org/10.5281/zenodo.18881624
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Quality of Life Analysis in SRC + HIPEC Patients: Single-Center Experience2026
  2. 2Quality of life following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a Canadian experience2025
  3. 3Evaluation of the Impact of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) on Long-Term Survival and Morbidity Profile: A Systematic Review of the Peritoneal Carcinomatosis Management2026 · 1 citations
  4. 4Hyperthermic Intraperitoneal Chemotherapy (HIPEC) vs. Postoperative Intraperitoneal (IP) Chemotherapy - Impact on Health-Related Quality of Life in Primary Ovarian Cancer Patients after Cytoreductive Surgery2024 · 1 citations
  5. 5SP6.03 A Systematic Review of Laparoscopic Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy2025