Endoscopic Posterior Nasal Neurectomy Versus Radiofrequency Ablation in Refractory Allergic Rhinitis: A 2-Year Randomized Controlled Trial of Clinical Outcomes and Immunomodulatory Responses.

Rui Zheng; X K Huang; Shuo Wu; Z H Shi; Kai Wang; Huijun Qiu; Tian Yuan; Chuanliang Zhao; Jianhui Zhao; W H Wang; Zhe Xiao; Jianfeng Liu; Shaoqing Yu; QinTai Yang

doi:10.1002/alr.70126

March 5, 2026

Endoscopic Posterior Nasal Neurectomy Versus Radiofrequency Ablation in Refractory Allergic Rhinitis: A 2-Year Randomized Controlled Trial of Clinical Outcomes and Immunomodulatory Responses.

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Key Points

To compare the clinical outcomes and immunomodulatory effects of endoscopic posterior nasal neurectomy and radiofrequency ablation in patients with refractory allergic rhinitis.
Conducted a 2-year randomized controlled trial.
Compared two treatment techniques: endoscopic nasal neurectomy and radiofrequency ablation.
Evaluated clinical outcomes and immunomodulatory responses over the study duration.
Both techniques are effective and safe for managing refractory allergic rhinitis over 2 years.
Neurectomy achieves superior and sustained control of rhinorrhea, nasal congestion, and itching compared to ablation.
Overall outcomes between the two methods are comparable but suggest benefits of individualizing treatment based on symptoms.

Implication

Randomized controlled trial shows neurectomy provides better symptom control in refractory allergic rhinitis, suggesting tailored treatments.

Abstract

Both techniques are effective and safe for refractory AR over 2 years. Although overall outcomes are comparable, neurectomy offers superior and sustained control of rhinorrhea, nasal congestion, and nasal itching. Treatment can be individualized based on symptom profile.

Discussion

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Cite This Study

Zheng et al. (2026) studied this question.

synapsesocial.com/papers/69abc2855af8044f7a4ec3f3 https://doi.org/10.1002/alr.70126

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Endoscopic Posterior Nasal Neurectomy Versus Radiofrequency Ablation in Refractory Allergic Rhinitis: A 2-Year Randomized Controlled Trial of Clinical Outcomes and Immunomodulatory Responses.

Key Points

Implication

Abstract

Discussion

Cite This Study

Endoscopic Posterior Nasal Neurectomy Versus Radiofrequency Ablation in Refractory Allergic Rhinitis: A 2-Year Randomized Controlled Trial of Clinical Outcomes and Immunomodulatory Responses.

Key Points

Implication

Abstract

Discussion

Cite This Study

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