Synthesis of regioselective 9-selenabicyclo derivatives, indicating new methods for functional group incorporation with selenium.
The transannular addition reaction of selenium dichloride and dibromide to 1,3- cyclooctadiene was carried out for the first time. Based on this reaction, regio- and stereoselective approaches to new 2,3- bifunctional derivatives of 9- selenabicyclo[4.2.1]nonane with endo- exo and endo- endo stereochemistry have been developed. Conditions for stereoselective transannular anti, syn- and anti, anti- addition reactions have been found. A method for the sequential introduction of two different functional groups into the 9- selenabicyclo[4.2.1]nonane structure has been developed.
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M. V. Musalov (2025) studied this question.
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