Validating antibody characterization improves SGLT2 detection in kidney tissues, implying better translational studies.
HPA041603 consistently detected SGLT2 in rodent and human kidney tissues, whereas other antibodies showed limited specificity. Knockout-based antibody validation and optimized experimental conditions are essential for accurate interpretation of SGLT2 protein expression in experimental and translational studies.
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Hirose et al. (2026) studied this question.
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