Observational study shows changes in atherosclerosis and inflammation in bipolar disorder, indicating different vascular risks compared to schizophrenia.
Even physically healthy patients with BPD and SCZ exhibit accelerated atherosclerosis before geriatric age, reflected by increased cIMT. The association between hs-CRP and cIMT is observed in BPD, but not in SCZ, suggesting a greater role of chronic low-grade inflammation in BPD-related early vascular changes.
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Tsai et al. (2026) studied this question.
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