Support for deprescribing in European clinical practice guidelines: a systematic review

Deprescribing remains underrepresented in European clinical guidelines. There is an urgent need to shift from a disease-centred model to patient-centred care, with guidelines that provide clear, evidence-based strategies to discontinue medications that no longer offer clinical benefit. Scientific societies should lead to the development of recommendations that promote safe, rational and personalised prescribing, ensuring real benefits for patients while minimising risks. The entire process must be individualised and necessarily involve shared decision-making with patients, families and caregivers.