Adjunctive Therapeutic Plasma Exchange in Refractory Adult-Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single-Center Experience.

Key Points

• To evaluate the effectiveness of adjunctive therapeutic plasma exchange in patients with refractory adult-onset still's disease and secondary macrophage activation syndrome.
• Single-center retrospective analysis of patients treated with TPE.
• Assessment of clinical and biochemical parameters pre- and post-treatment.
• Focus on outcomes related to refractory symptoms and macrophage activation syndrome.
• Rapid clinical improvement observed post-TPE treatment.
• Significant biochemical improvement noted following the intervention.