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March 8, 2026Journal of InfectionOpen Access

Advancing the 2030 NTDs Roadmap Targets: A Scoping Review of Environmental DNA/RNA Applications in Neglected Tropical Diseases

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Authors

JHJian HeTLTianyun LiJZJinxin Zheng

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Overview

This scoping review evaluates environmental DNA applications in neglected tropical diseases, suggesting optimization strategies for effective surveillance.

Key Points

  • The review aims to assess the application and effectiveness of environmental DNA/RNA technology in neglected tropical diseases.
  • Conducted systematic literature search across four English and one Chinese database (2002–2024)
  • Screened 71 studies that met inclusion criteria
  • Synthesis of real-world field applications of environmental DNA technology
  • Identified 6 standardized applications for environmental DNA studies in neglected tropical diseases
  • Demonstrated moderate concordance with conventional detection methods
  • Showed superior sensitivity in detecting pathogens and hosts compared to traditional methods

Cite This Study

He et al. (2026) studied this question.

synapsesocial.com/papers/69ada892bc08abd80d5bb9c5https://doi.org/10.1016/j.jinf.2026.106716
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