Evolution of Nerve Conduction Demyelinating Parameters Between Baseline and Treatment Cessation May Not Be Predictive of Relapse in IVIg-Responsive CIDP Patients.

Marine Le Vavasseur; Capucine Blaise; Isabelle Cordelle; Pauline Reach; Sahar Chakroun; Nathalie Kubis; Pierre Lozeron

doi:10.1002/mus.70199

March 6, 2026

Evolution of Nerve Conduction Demyelinating Parameters Between Baseline and Treatment Cessation May Not Be Predictive of Relapse in IVIg-Responsive CIDP Patients.

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Key Points

The research aims to determine the predictive ability of follow-up nerve conduction studies for relapse in CIDP patients receiving IVIg treatment.
Analyzed nerve conduction studies in IVIg-responsive CIDP patients
Monitored changes in demyelination parameters between baseline and treatment cessation
Evaluated the relationship between these studies and relapse rates
No predictive value of follow-up nerve conduction studies on relapse was demonstrated
Indicated a need to explore additional biomarkers for better prediction

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Implication

Observational study on relapse prediction in IVIg-responsive CIDP patients highlights need for alternative biomarkers.

Abstract

In our population of IVIg responsive CIDP patients, we were unable to demonstrate the predictive value of follow-up nerve conduction studies alone for the risk of relapse. Looking at other biomarkers alone or in combination with NCS is necessary.

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Vavasseur et al. (2026) studied this question.

synapsesocial.com/papers/69ada8a1bc08abd80d5bbbb9 https://doi.org/10.1002/mus.70199

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Evolution of Nerve Conduction Demyelinating Parameters Between Baseline and Treatment Cessation May Not Be Predictive of Relapse in IVIg-Responsive CIDP Patients.

Key Points

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Implication

Abstract

Discussion

Cite This Study

Evolution of Nerve Conduction Demyelinating Parameters Between Baseline and Treatment Cessation May Not Be Predictive of Relapse in IVIg-Responsive CIDP Patients.

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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