Endothelial activation and stress index (EASIX) as a predictor of acute kidney injury in patients undergoing transcatheter aortic valve replacement: A retrospective cohort study.

Figures

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  Figure 1.. EASIX scores according to CIN groups. EASIX scores were compared between patients with <25% increase in serum creatinine (CIN negative) and those with ≥25% increase (CIN positive). The box plots illustrate the median (line within the box), interquartile range (box), and range (whiskers). Circles and asterisks denote outliers. CIN = contrast-induced nephropathy, EASIX = Endothelial Activation and Stress Index.

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  Figure 2.. Standardized baseline creatinine, platelet count, and LDH values according to CIN groups. Box plots represent z-scores for baseline creatinine (blue), platelet count (green), and lactate dehydrogenase (purple) among patients with <25% increase in serum creatinine (CIN negative) versus ≥25% increase (CIN positive). Each box denotes the interquartile range, horizontal lines within boxes indicate the median, and whiskers depict the range. Circles indicate outliers. CIN = contrast-induced nephropathy, LDH = lactate dehydrogenase, PLT = platelets.

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  Figure 3.. ROC curve of the EASIX score for predicting CIN. The receiver operating characteristic (ROC) analysis demonstrates the ability of the EASIX score to discriminate between patients who develop contrast-induced nephropathy (CIN+) and those who do not. The area under the curve (AUC) is 0.910, with P < .001, indicating excellent diagnostic performance. AUC = area under the curve, CIN = contrast-induced nephropathy, EASIX = Endothelial Activation and Stress Index, ROC = receiver operating characteristic.