Systematic review explores molecular subtype associations with survival prognosis in small cell lung cancer, highlighting knowledge gaps.
This is one of the first comprehensive systematic reviews to explore the relationship between molecular subtypes and survival prognosis in SCLC. Future high-quality studies employing standardized subtype definitions are warranted to validate these prognostic associations and enable definitive conclusions. Furthermore, emerging multi-omics and integrated spatial analyses have revealed novel subtypes and predictors, which are significantly associated with survival prognosis.
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Li et al. (2026) studied this question.
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