Dehydrogenase-like stacked MoS2 nanozymes for cancer treatment through disrupting tricarboxylic acid cycle

Key Points

• The research aims to explore the effects of dehydrogenase-like MoS2 nanozymes on cancer cell metabolism, particularly the tricarboxylic acid cycle.
• Utilized MoS2 nanozymes to perturb tumor metabolic processes.
• Analyzed the impact on the tricarboxylic acid cycle in cancer cells.
• Conducted various metabolic assays to assess enzyme activity.
• MoS2 nanozymes effectively disrupted the tricarboxylic acid cycle.
• This disruption led to reduced energy production in tumor cells.
• The study indicates a potential new therapeutic avenue for cancer treatment.