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January 1, 2017Cellular Physiology and BiochemistryOpen Access

Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction

Krishna M. Boini Tahir Hussain Pin‐Lan Li Sai S. Koka

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Abstract

The formation and activation of NLRP3 inflammasomes by TMAO may be an important initiating mechanism to turn on the endothelial inflammatory response leading to endothelial dysfunction.

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Boini et al. (2017) studied this question.

synapsesocial.com/papers/69af5dc5b6826013fc880d92 https://doi.org/10.1159/000484623

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