Why the study?
Does race/ethnicity affect the appropriate Lipoprotein(a) cutoff value for coronary heart disease risk assessment?
Does race/ethnicity affect the appropriate Lipoprotein(a) cutoff value for coronary heart disease risk assessment?
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Lipoprotein(a) risk thresholds for coronary heart disease should be race-specific, with higher cutoffs (50 mg/dL) for white and Hispanic individuals compared to black individuals (30 mg/dL).
Our findings suggest that the 30 mg/dL cutoff for Lp(a) is not appropriate in white and Hispanic individuals, and the higher 50 mg/dL cutoff should be considered. In contrast, the 30 mg/dL cutoff remains suitable in black individuals. Further research is necessary to develop the most clinically useful Lp(a) cutoff values in individual races/ethnicities.
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Guan et al. (2015) studied this question.
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