Systematic review explores how pollution affects skin disease via inflammatory pathways, suggesting new preventive healthcare approaches.
Environmental pollution is increasingly implicated in acne pathogenesis through oxidative stress, barrier disruption and inflammatory signalling, with similar mechanisms contributing to a broader spectrum of dermatologic disease. Emerging evidence also highlights pollution-induced alterations in the cutaneous microbiome, further amplifying immune dysregulation and barrier impairment, while chronic exposure interacts with ultraviolet radiation to accelerate photoaging and carcinogenesis. Recognising pollution as a modifiable upstream determinant of skin disease reframes dermatology’s role in advancing preventive care, sustainability and environmentally responsible healthcare delivery.
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Nikookam et al. (2026) studied this question.
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