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March 10, 2026BMC MicrobiologyOpen Access

Genophenotypic insights into biocontrol and growth-promoting mechanisms of Bacillus velezensis BV25 against tomato Fusarium wilt

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Authors

TXTian XuMLMing LiXDXin Dong

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Overview

Research uncovers Bacillus velezensis BV25's biocontrol and growth-promoting effects in tomatoes, suggesting sustainable solutions for Fusarium wilt management.

Key Points

  • This research aims to explore the biocontrol and growth-promoting mechanisms of Bacillus velezensis BV25 against tomato Fusarium wilt.
  • Conducted in vitro assays to assess FOL growth inhibition by BV25 and its extracts.
  • Performed greenhouse trials measuring the effects of BV25 fermentation broth on plant health and disease severity.
  • Analyzed defense enzyme activities in plants treated with BV25.
  • Executed complete genome sequencing of B. velezensis BV25 and performed ANI analysis to confirm species designation.
  • Identified secondary metabolite biosynthetic gene clusters and genes related to plant growth promotion.
  • Bacillus velezensis BV25 significantly inhibited Fusarium oxysporum growth in vitro.
  • The efficacy of BV25 extracts was found to be dose-dependent.
  • In greenhouse trials, BV25 reduced disease severity and improved plant growth even without the pathogen.
  • Treatment with BV25 heightened defense enzyme activities, indicating induced plant defense mechanisms.
  • A diverse array of genes related to antifungal activity and plant growth promotion was identified in BV25's genome.

Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/69af94c970916d39fea4bac9https://doi.org/10.1186/s12866-026-04919-7
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